| LLL-12 |
Influence on cell proliferation |
Wound healing assay |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Wound healing assay |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Wound healing assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Wound healing assay |
20.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability |
MTT |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability |
MTT |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability |
MTT |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability |
MTT |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability |
MTT |
20.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability in STAT3 transfected cells |
MTT |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability in STAT3 transfected cells |
MTT |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell viability in STAT3 transfected cells |
MTT |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
| LLL-12 |
Influence on tumor growth |
Tumor volume |
2.50 mg/kg |
U87 |
Mus musculus |
|
|
|
| LLL-12 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
U87 |
Mus musculus |
|
|
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
