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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
CADPE Influence on endothelial cells Immunohistochemistry 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice p-STAT3
CADPE Influence on endothelial cells Immunohistochemistry 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on endothelial cells Immunohistochemistry 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on protein levels in tumor tissue Western Blot 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice p-STAT3 (Tyr-705)
CADPE Influence on protein levels in tumor tissue Western Blot 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on protein levels in tumor tissue Western Blot 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on RNA levels in tumor tissue RT-PCR 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on RNA levels in tumor tissue RT-PCR 5.00 mg/kg Caki-I(xenograft) Mus musculus nude mice
CADPE Influence on cell proliferation MTT 25.00 µM Huh7 Homo sapiens
CADPE Influence on cell proliferation MTT 50.00 µM Huh7 Homo sapiens
CADPE Influence on cell proliferation MTT 100.00 µM Huh7 Homo sapiens
CADPE Influence on transcriptional activity in presence of IL-6 RT-PCR 100.00 µM Huh7 Homo sapiens
CADPE Influence on transcriptional activity in presence of IL-6 RT-PCR 100.00 µM Huh7 Homo sapiens
CADPE Influence on protein activity in presence of IL-6 Western Blot 15.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on protein activity in presence of IL-6 Western Blot 30.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on protein activity in presence of IL-6 Western Blot 50.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on protein activity in presence of IL-6 Western Blot 100.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on protein activity in presence of IL-6 Western Blot 15.00 µM Huh7 Homo sapiens STAT3
CADPE Influence on protein activity in presence of IL-6 Western Blot 30.00 µM Huh7 Homo sapiens STAT3
CADPE Influence on protein activity in presence of IL-6 Western Blot 50.00 µM Huh7 Homo sapiens STAT3
CADPE Influence on protein activity in presence of IL-6 Western Blot 100.00 µM Huh7 Homo sapiens STAT3
CADPE Influence on protein activity in presence of IL-6 Western Blot 50.00 µM COS7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on protein activity in presence of IL-6 Western Blot 50.00 µM COS7 Homo sapiens STAT3
CADPE Influence on protein activity in presence of IL-6 Western Blot 50.00 µM COS7 Homo sapiens
CADPE Influence on STAT3-dependent expression Western Blot 50.00 µM Huh7 Homo sapiens
CADPE Influence on STAT3-dependent expression Western Blot 50.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on STAT3-dependent expression Western Blot 50.00 µM Huh7 Homo sapiens STAT3
CADPE Influence on STAT3-dependent expression in presence of IL-6 Luciferase activity 50.00 µM COS7 Homo sapiens
CADPE Influence on STAT3-dependent expression in presence of IL-6 Luciferase activity 50.00 µM Huh7 Homo sapiens
CADPE Influence on STAT3 recruitment Immunoprecipitation 50.00 µM Huh7 Homo sapiens p-STAT3 (Tyr-705)
CADPE Influence on STAT3 recruitment Immunoprecipitation 50.00 µM Huh7 Homo sapiens p-STAT5 (Tyr-694/699)
CADPE Influence on STAT3 recruitment Immunoprecipitation 50.00 µM Huh7 Homo sapiens
CADPE Influence on STAT3 recruitment Immunoprecipitation 50.00 µM Huh7 Homo sapiens
CADPE Influence on cell differentiation TRAP assay 0.10 µM BMM Mus musculus
CADPE Influence on cell differentiation TRAP assay 0.50 µM BMM Mus musculus
CADPE Influence on cell differentiation TRAP assay 1.00 µM BMM Mus musculus
CADPE Influence on cell differentiation TRAP assay 2.50 µM BMM Mus musculus
CADPE Influence on cell differentiation TRAP assay 5.00 µM BMM Mus musculus
CADPE Influence on cell differentiation TRAP assay 0.10 µM RAW264.7 Mus musculus
CADPE Influence on cell differentiation TRAP assay 0.50 µM RAW264.7 Mus musculus
CADPE Influence on cell differentiation TRAP assay 1.00 µM RAW264.7 Mus musculus
CADPE Influence on cell differentiation TRAP assay 2.50 µM RAW264.7 Mus musculus
CADPE Influence on cell differentiation TRAP assay 5.00 µM RAW264.7 Mus musculus
CADPE Influence on cell differentiation Actin-ring formation 5.00 µM BMM Mus musculus
CADPE Influence on cell proliferation MTT 0.50 µM BMM Mus musculus
CADPE Influence on cell proliferation MTT 1.00 µM BMM Mus musculus
CADPE Influence on cell proliferation MTT 5.00 µM BMM Mus musculus
CADPE Influence on cell proliferation MTT 10.00 µM BMM Mus musculus
CADPE Influence on cell proliferation MTT 25.00 µM BMM Mus musculus
CADPE Influence on osteoclast bone resorption Mayer’s hematoxylin 5.00 µM BMM Mus musculus