| C188 |
Influence on tumor growth |
Mammosphere forming efficiency (MSFE) |
10.00 µM |
SUM159 |
Homo sapiens |
|
|
|
| C188 |
Influence on tumor growth |
Mammosphere forming efficiency (MSFE) |
10.00 µM |
BT549 |
Homo sapiens |
|
|
|
| C188 |
Influence on tumor growth |
Tumor volume |
12.50 mg/kg |
BCM2665(xengraft) |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
Influence on tumor growth |
MSFE |
12.50 mg/kg |
BCM2665(xengraft) |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
Influence on tumor growth |
Western Blot |
12.50 mg/kg |
BCM2665(xengraft) |
Mus musculus |
SCID Beige mice |
p-STAT3 |
|
| C188 |
Influence on tumor growth |
Western Blot |
12.50 mg/kg |
BCM2665(xengraft) |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
Influence on tumor growth |
Immunohistochemistry |
12.50 mg/kg |
BCM2665(xengraft) |
Mus musculus |
SCID Beige mice |
p-STAT3 |
|
| C188 |
TIC marker measurement |
Tumor volume |
12.50 mg/kg |
MC1 |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
TIC marker measurement |
FACS |
12.50 mg/kg |
MC1 |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
Influence on tumor growth |
Kaplan Meier recurence |
12.50 mg/kg |
2665A (ER/PgR/HER2-negative and p-Stat3-positive) |
Mus musculus |
SCID Beige mice |
|
|
| C188 |
Structure comparision |
Structure Activity Realtionship SAR |
N/A N/A |
|
|
|
|
|
| C188 |
Biacore sensorchip-immobilized phosphododecapeptide ligand |
SPR |
N/A µM |
|
Homo sapiens |
|
STAT3 |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
1.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
3.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
10.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
30.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
100.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
300.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
1.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
3.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
10.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
30.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
100.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Phosphoflow |
300.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Mean fluorescence |
N/A N/A |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Mean fluorescence |
N/A N/A |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.10 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.30 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
1.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
3.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
10.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
100.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.10 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.30 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
1.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
3.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
10.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
100.00 µM |
Kasumi-1 |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.10 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.30 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
1.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
3.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
10.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
100.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT3 (Tyr-705) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.10 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
0.30 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
1.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
3.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
10.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
| C188 |
Influence on proteins activity |
Luminex |
100.00 µM |
UM-SCC-17B |
Homo sapiens |
|
p-STAT1 (Tyr-701) |
|
