| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
HepG2 |
Homo sapiens |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
HepG2 |
Homo sapiens |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
HepG2 |
Homo sapiens |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
HepG2 |
Homo sapiens |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
p-STAT3(nuclear) |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
p-STAT3(cytoplasm) |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
HepG2 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.30 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.10 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.30 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
fibroblast-like synoviocytes (FLS) |
Homo sapiens (patient) |
|
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 in tissue |
Western Blot |
0.20 µM |
Astrocytes |
Rattus norvegicus |
Sprague–Dawley |
p-STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of IL-6 in tissue |
Western Blot |
0.20 µM |
Astrocytes |
Rattus norvegicus |
Sprague–Dawley |
STAT3 |
|
| AS1810722 |
Influence on protein activity in presence of FBS |
Western Blot |
0.10 µM |
HUVECS |
Homo sapiens (patient) |
|
|
|
| AS1810722 |
Influence on protein activity in presence of FBS |
Western Blot |
0.30 µM |
HUVECS |
Homo sapiens (patient) |
|
|
|
| AS1810722 |
Influence on protein activity in presence of FBS |
Western Blot |
0.50 µM |
HUVECS |
Homo sapiens (patient) |
|
|
|
| AS1810722 |
Influence on hepatic metabolism |
LC-MS; HPLC |
5.00 µM |
HLM |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
1.00 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
1.00 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
10.00 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
10.00 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.03 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.10 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.30 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
