AG490 |
Influence on EPO administration and apoptosis |
TUNEL |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on EPO in ischemic quadriceps |
Hematoxylin and eosin staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on EPOR activity in presence of CLI and/or EPO |
Immunohistochemical staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on blood flow recovery in presence of CLI and/or EPO |
Laser Doppler |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on vessel density in presence of CLI and/or EPO |
Immunohistochemical staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on cell viability |
MMT |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on gene expression levels |
RT-qPCR |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on gene expression levels |
RT-qPCR |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on protein activity |
Immunocytochemistry |
20.00 µM |
SW1990 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
SW1990 |
Homo sapiens |
|
p-STAT3 |
|
AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
SW1990 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Influence on cell motility |
Invasion assay |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
|
Western Blot |
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
|
Western Blot |
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
|
RT-qPCR |
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
|
RT-qPCR |
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT3 |
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein activity in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein motility in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein motility in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein motility in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein motility in presence of SAH |
Western Blot |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on protein motility in presence of SAH |
Immunofluorescence |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Influence on neuronal apoptosis |
TUNEL |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|