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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AG490 Influence on EPO administration and apoptosis TUNEL 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on EPO in ischemic quadriceps Hematoxylin and eosin staining 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on gene expression levels in presence of CLI and/or EPO RT-qPCR 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of CLI and/or EPO Western Blot 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on EPOR activity in presence of CLI and/or EPO Immunohistochemical staining 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on blood flow recovery in presence of CLI and/or EPO Laser Doppler 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on vessel density in presence of CLI and/or EPO Immunohistochemical staining 3.00 mg/kg quadriceps Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on cell viability MMT 20.00 µM SW1990 Homo sapiens
AG490 Influence on gene expression levels RT-qPCR 20.00 µM SW1990 Homo sapiens
AG490 Influence on gene expression levels RT-qPCR 20.00 µM SW1990 Homo sapiens
AG490 Influence on protein activity Immunocytochemistry 20.00 µM SW1990 Homo sapiens STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens p-STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens STAT3
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens
AG490 Influence on protein activity Western Blot 20.00 µM SW1990 Homo sapiens
AG490 Influence on cell motility Invasion assay 20.00 µM SW1990 Homo sapiens
AG490 Western Blot 25.00 μM/L Pancreatic Acinar Cells Rattus norvegicus Sprague-Dawley (SD) rats STAT3
AG490 Western Blot 25.00 μM/L Pancreatic Acinar Cells Rattus norvegicus Sprague-Dawley (SD) rats
AG490 RT-qPCR 25.00 μM/L Pancreatic Acinar Cells Rattus norvegicus Sprague-Dawley (SD) rats STAT3
AG490 RT-qPCR 25.00 μM/L Pancreatic Acinar Cells Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats p-STAT3
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats STAT3
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein activity in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein motility in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein motility in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein motility in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein motility in presence of SAH Western Blot 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on protein motility in presence of SAH Immunofluorescence 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats
AG490 Influence on neuronal apoptosis TUNEL 10.00 µM Brain tissue Rattus norvegicus Sprague-Dawley (SD) rats