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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (Y705) (nucleus)
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM TOV-21G Homo sapiens STAT3 (nucleus)
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM A2780 Homo sapiens p-STAT3 (Y705) (nucleus)
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM A2780 Homo sapiens STAT3 (nucleus)
3,3 diindolylmethane Influence on protein translocation Western Blot 75.00 µM A2780 Homo sapiens
3,3 diindolylmethane Influence on protein-DNA interaction EZ-TFA transcription factor colorimetric assay 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM OVCAR-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM TOV-21G Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM A2780 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis in presence of IL-6 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis in presence of IL-6 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on apoptosis in cells overexpressing STAT3 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM OVCAR-429 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on cell motility Aortic ring assay 50.00 µM rat thoracic aorta Rattus norvegicus
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens