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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
inS3-54A18 Influence on protein binding to DNA EMSA 50.00 µM H1299 Homo sapiens STAT3
inS3-54A18 Influence on protein binding to DNA EMSA 100.00 µM H1299 Homo sapiens STAT3
inS3-54A18 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM A549 Homo sapiens STAT3
inS3-54A18 Influence on protein activity Immunohistochemistry 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID STAT3
inS3-54 Infleuence on protein activity Western Blot 0.25 µM RAW 264.7 Mus musculus p-STAT3 (Ser727)
inS3-54 Infleuence on protein activity Western Blot 0.50 µM RAW 264.7 Mus musculus p-STAT3 (Ser727)
inS3-54 Infleuence on protein activity Western Blot 1.00 µM RAW 264.7 Mus musculus p-STAT3 (Ser727)
inS3-54 Infleuence on protein activity Western Blot 2.00 µM RAW 264.7 Mus musculus p-STAT3 (Ser727)
inS3-54 Infleuence on protein activity Western Blot 3.00 µM RAW 264.7 Mus musculus p-STAT3 (Ser727)
inS3-54 Infleuence on protein activity Western Blot 0.25 µM RAW 264.7 Mus musculus p-STAT3 (Tyr705)
inS3-54 Infleuence on protein activity Western Blot 0.50 µM RAW 264.7 Mus musculus p-STAT3 (Tyr705)
inS3-54 Infleuence on protein activity Western Blot 1.00 µM RAW 264.7 Mus musculus p-STAT3 (Tyr705)
inS3-54 Infleuence on protein activity Western Blot 2.00 µM RAW 264.7 Mus musculus p-STAT3 (Tyr705)
inS3-54 Infleuence on protein activity Western Blot 3.00 µM RAW 264.7 Mus musculus p-STAT3 (Tyr705)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM MDA-MB-231 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM MDA-MB-231 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM MDA-MB-231 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM MDA-MB-231 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (chromatin bound)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (chromatin bound)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM MDA-MB-231 Homo sapiens STAT3 (chromatin bound)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM MDA-MB-231 Homo sapiens STAT3 (chromatin bound)