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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of IL-6 Western Blot 0.10 µM U266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of IL-6 Western Blot 0.30 µM U266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of IL-6 Western Blot 1.00 µM U266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of IL-6 Western Blot 3.00 µM U266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of IL-6 Western Blot 10.00 µM U266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 0.10 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 0.30 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 1.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 3.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on expression of proteins downstream target genes Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on expression of proteins downstream target genes Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on expression of proteins downstream target genes Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 0.10 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 0.30 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 1.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 3.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5A