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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Co-immunoprecipitation 5.00 µM MDA-MB-468 Homo sapiens IP:EGFR IB:STAT3
Withacnistin Influence on protein activity Co-immunoprecipitation 5.00 µM MDA-MB-468 Homo sapiens IP:EGFR IB:STAT5
Withacnistin Influence on protein activity Co-immunoprecipitation 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Co-immunoprecipitation 5.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Co-immunoprecipitation 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM U-266 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM U-266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM RPMI-8226 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM RPMI-8226 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 5.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.30 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 1.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 3.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 0.10 µM U-266 Homo sapiens p-STAT3