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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
WP1066 Influence on protein activity Western Blot 2.50 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude p-STAT3
WP1066 Influence on protein activity Western Blot 1.25 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16EGFRvIII Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 1.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice p-STAT3