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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
WP1066 Influence on protein activity Western Blot 2.50 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM Caki-1 Homo sapiens p-STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM 786-O Homo sapiens p-STAT3
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude p-STAT3
WP1066 Influence on protein activity Western Blot 1.25 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM A375 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16 Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16EGFRvIII Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 1.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 2.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens p-STAT3
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice p-STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM Caki-1 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM Caki-1 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM 786-O Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM 786-O Homo sapiens STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM Caki-1 Homo sapiens STAT3
WP1066 Influence on protein activity in hypoxia Western Blot 5.00 µM 786-O Homo sapiens STAT3
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude STAT3
WP1066 Influence on protein activity Western Blot 1.25 µM A375 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 2.50 µM A375 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM A375 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16 Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM B16EGFRvIII Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 1.00 µM AGS Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 2.00 µM AGS Homo sapiens STAT3
WP1066 Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens STAT3
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice STAT3