| WP1066 |
Influence on cell viability |
MTS |
10.00 µM |
Caki-1 |
Homo sapiens |
|
|
|
| WP1066 |
Influence on cell viability |
MTS |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
| WP1066 |
Influence on tumor growth |
Percent survival |
10.00 mg/kg |
B16EGFRvIII (xenograft) |
Mus musculus |
C57BL/6J |
|
|
| WP1066 |
Influence on cell tumor growth |
Tumor size |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on cell proliferation on tumor tissue |
Immunostaining |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on cell apoptosis on tumor tissue |
Immunostaining |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
STAT3 |
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
p-STAT3 |
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
gp130757FF tumor tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on pro-inflammatory gene expression |
Real-time qPCR |
10.00 mg/kg |
antral stomach tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on pro-inflammatory gene expression |
Real-time qPCR |
10.00 mg/kg |
antral stomach tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on pro-inflammatory gene expression |
Real-time qPCR |
10.00 mg/kg |
antral stomach tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on pro-inflammatory gene expression |
Real-time qPCR |
10.00 mg/kg |
antral stomach tissue |
Mus musculus |
gp130 757FF mice |
|
|
| WP1066 |
Influence on pro-inflammatory gene expression |
Real-time qPCR |
10.00 mg/kg |
antral stomach tissue |
Mus musculus |
gp130 757FF mice |
|
|
