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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 50.00 nM HOS Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 100.00 nM HOS Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 200.00 nM HOS Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 50.00 nM MG63.2 Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 100.00 nM MG63.2 Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 200.00 nM MG63.2 Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 50.00 nM HOS Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 100.00 nM HOS Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 200.00 nM HOS Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 50.00 nM MG63.2 Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 100.00 nM MG63.2 Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 200.00 nM MG63.2 Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens STAT3(nucleus)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens STAT3(nucleus)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens STAT3(cytoplasm)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens STAT3(cytoplasm)
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:VEGF
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:VEGF
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:VEGF