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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on cell viability MTS Assay 50.00 nM hFOB1.19 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM hFOB1.19 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 200.00 nM hFOB1.19 Homo sapiens
Toosendanin Influence on cell viability in STAT3 transfected cells MTS Assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Colony formation assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Colony formation assay 25.00 nM HOS Homo sapiens
Toosendanin Influence on cell motility Colony formation assay 25.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Colony formation assay 25.00 nM MG63 Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 200.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 50.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 200.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Tube formation assay 50.00 nM HUVEC Homo sapiens
Toosendanin Influence on cell motility Tube formation assay 100.00 nM HUVEC Homo sapiens
Toosendanin Influence on cell motility Tube formation assay 200.00 nM HUVEC Homo sapiens
Toosendanin Influence on cell motility Invasion assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 200.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 25.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Invasion assay 50.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Invasion assay 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Invasion assay 200.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 200.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM MG63.2 Homo sapiens