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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on cell viability MTS Assay 100.00 nM hFOB1.19 Homo sapiens
Toosendanin Influence on cell viability in STAT3 transfected cells MTS Assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility Tube formation assay 100.00 nM HUVEC Homo sapiens
Toosendanin Influence on cell motility Invasion assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM MG63.2 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM HCT116 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM SGC7901 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM SKOV3 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM MDA-MB-231 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM DU145 Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM Hela Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM SW-1990 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM HCT116 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM HCT116 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM HCT116 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM SGC7901 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SGC7901 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SGC7901 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens