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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on cell apoptosis Flow cytometry 20.00 µM Jurkat Homo sapiens
STX-0119 Influence on cell apoptosis Flow cytometry 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on cell apoptosis Flow cytometry 36.00 µM U937 Homo sapiens
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3 (nucleus)
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3 (cytoplasm)
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens STAT3 (nucelus)
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens STAT3 (cytoplam)
STX-0119 Influence on protein activity FRET 10.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 Influence on protein activity FRET 20.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 Influence on protein activity FRET 50.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 Influence on protein activity FRET 10.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 Influence on protein activity FRET 20.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 Influence on protein activity FRET 50.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 Influence on protein activity Chromatin immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Chromatin immunoprecipitation 20.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Chromatin immunoprecipitation 50.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity in precence of IFNα Western Blot 25.00 µM HMEC Homo sapiens p-STAT1