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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 1.00 µM MDA-MB-231 Homo sapiens Ac-STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 2.00 µM MDA-MB-231 Homo sapiens Ac-STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 5.00 µM MDA-MB-231 Homo sapiens Ac-STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 10.00 µM MDA-MB-231 Homo sapiens Ac-STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 1.00 µM MDA-MB-231 Homo sapiens STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 2.00 µM MDA-MB-231 Homo sapiens STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 5.00 µM MDA-MB-231 Homo sapiens STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 10.00 µM MDA-MB-231 Homo sapiens STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 1.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 2.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 5.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 10.00 µM MDA-MB-231 Homo sapiens p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on protein activity Western Blot 10.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens p-STAT1(701)
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens p-STAT1(701)
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens p-STAT1(701)
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 1.00 µM MDA-MB-231 Homo sapiens STAT1
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 2.00 µM MDA-MB-231 Homo sapiens STAT1
STAT3-IN-1 (compound 7d) Influence on expression of STAT target genes Western Blot 5.00 µM MDA-MB-231 Homo sapiens STAT1
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg MDA-MB-231(xenograft) Mus musculus p-STAT3(Y705)