| STAT3-IN-1 (compound 7d) |
Influence on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
Ac-STAT3 |
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| STAT3-IN-1 (compound 7d) |
Influence on cell apoptosis |
Flow cytometry- annexin V binding and propidium iodide staining |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| STAT3-IN-1 (compound 7d) |
Influence on cell proliferation |
Colony formation assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| STAT3-IN-1 (compound 7d) |
Influence on tumor growth |
Mice body weight |
10.00 mg/kg |
MDA-MB-231(xenograft) |
Mus musculus |
|
|
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
MDA-MB-231(xenograft) |
Mus musculus |
|
p-STAT3(Y705) |
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
MDA-MB-231(xenograft) |
Mus musculus |
|
STAT3 |
|
| STAT3-IN-1 (compound 7d) |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 mg/kg |
MDA-MB-231(xenograft) |
Mus musculus |
|
|
|
