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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 8.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 8.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA EMSA 8.00 µM U251MG Homo sapiens STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 8.00 µM U373MG Homo sapiens STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 8.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 8.00 µM DU145 Homo sapiens STAT3:STAT3
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 8.00 µM NIH3T3 pLucTKS3 Mus musculus
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 8.00 µM NIH3T3 pLucSRE Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM MDA-MB-231 Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM DU145 Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM Panc-1 Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM U251MG Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM U373MG Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM NIH3T3 Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM A2780S Homo sapiens
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM MCF-7 Homo sapiens
SH5-07 Influence on cell cycle Flow cytometry- propodium iodide 8.00 µM MDA-MB-231 Homo sapiens
SH5-07 Influence on cell cycle Flow cytometry- propodium iodide 8.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell apoptosis Flow cytomentry- Annexin V 8.00 µM MDA-MB-231 Homo sapiens
SH5-07 Influence on cell apoptosis Flow cytomentry- Annexin V 8.00 µM U251MG Homo sapiens
SH5-07 Influence on cell apoptosis Flow cytomentry- Annexin V 8.00 µM MEF/ST3KO Mus musculus