| SH5-07 |
Influence on protein binding to DNA in presence of EGF |
EMSA |
3.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA in presence of EGF |
EMSA |
3.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
STAT1:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA in presence of EGF |
EMSA |
3.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
STAT1:STAT1 |
|
| SH5-07 |
Influence on protein binding to DNA in presence of EGF |
EMSA |
3.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
STAT5:STAT5 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
U251MG |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
U373MG |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
DU145 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
U87MG |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
SF295 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
U251MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
U251MG |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
U373MG |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
U373MG |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity in transfected cells |
Luciferase activity |
3.00 µM |
NIH3T3 pLucTKS3 |
Mus musculus |
|
|
|
| SH5-07 |
Infleunce on protein activity in transfected cells |
Luciferase activity |
3.00 µM |
NIH3T3 pLucSRE |
Mus musculus |
|
|
|
| SH5-07 |
Influence on cell motility |
Colony formation assay |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell motility |
Colony formation assay |
3.00 µM |
U251MG |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell motility |
Colony formation assay |
3.00 µM |
MEF/ST3KO |
Mus musculus |
|
|
|
| SH5-07 |
Influence on cell cycle |
Flow cytometry- propodium iodide |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell cycle |
Flow cytometry- propodium iodide |
3.00 µM |
MEF/ST3KO |
Mus musculus |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
3.00 µM |
U251MG |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
3.00 µM |
MEF/ST3KO |
Mus musculus |
|
|
|
| SH5-07 |
Influence on tumor growth |
Tumor size |
3.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
