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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 4.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 6.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability CyQUANT cell proliferation assay 10.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability Colony formation assay 1.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability Colony formation assay 3.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on cell viability Colony formation assay 5.00 µM MEF/ST3KO Mus musculus
SH4-54 Influence on tumor growth Tumor size 6.00 mg/kg U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on tumor growth Tumor size 6.00 mg/kg MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM U251MG (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 3.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 4.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice
SH4-54 Influence on protein activity in tumor tissue Western Blot 5.00 µM MDA-MB-231 (xenograft) Mus musculus athymic nude mice