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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
S3I-M2001 Influence on protein binding to DNA EMSA 10.00 µM Sf-9 Spodoptera frugiperda STAT3:STAT3
S3I-M2001 Influence on protein binding to DNA EMSA 10.00 µM Sf-9 Spodoptera frugiperda STAT3:STAT1
S3I-M2001 Influence on protein binding to DNA EMSA 10.00 µM Sf-9 Spodoptera frugiperda STAT1:STAT1
S3I-M2001 Influence on protein binding to DNA EMSA 10.00 µM NIH 3T3/v-Src Mus musculus STAT3:STAT3
S3I-M2001 Influence on protein binding to DNA EMSA 10.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
S3I-M2001 Influence on tumor growth Tumor volume 10.00 mg/kg MDA-MB-231 (xenograft) Mus musculus athymic nude mice