| Ponatinib |
Influence on tumor growth |
Tumor volume |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on tumor growth |
Tumor size |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
p-STAT3 (Y705) |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
