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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Ponatinib Influence on protein activity in presence of bFGF Western Blot 5.00 µM SH-SY5Y Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of bFGF Western Blot 10.00 µM SH-SY5Y Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of bFGF Western Blot 20.00 µM SH-SY5Y Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of bFGF Western Blot 2.00 µM SH-SY5Y Homo sapiens
Ponatinib Influence on protein activity in presence of bFGF Western Blot 5.00 µM SH-SY5Y Homo sapiens
Ponatinib Influence on protein activity in presence of bFGF Western Blot 10.00 µM SH-SY5Y Homo sapiens
Ponatinib Influence on protein activity in presence of bFGF Western Blot 20.00 µM SH-SY5Y Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM NGP Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM NGP Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM NGP Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM NGP Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM NGP Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on apoptotic protein activity in presence of Dox Western Blot 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice p-STAT3 (Y705)
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice STAT3
Ponatinib Influence on protein activity in tumor tissue Western Blot 15.00 mg/kg NB-19 (xenograft) Mus musculus NCr nude mice