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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DIFI Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DIFI Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DIFI Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM SW48 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM SW48 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.01 µM SW48 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 10.00 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 10.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 10.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens p-STAT3 (Y705)
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens STAT3
Ponatinib Influence on protein activity Western Blot 10.00 µM IMR-32 Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens
Ponatinib Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens