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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DIFI Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM SW48 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-6 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein translocation in presence of IL-11 Fluorescent staining 1.00 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on gene expression RT-qPCR 1.00 µM DIFI Homo sapiens
Ponatinib Influence on gene expression RT-qPCR 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on gene expression RT-qPCR 1.00 µM SW48 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM DIFI Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM SW48 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM CPP14 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM CPP19 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM CPP35 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM CACO2 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM LIM1215 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM LOVO Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM HI55 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM LIM2099 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM LIM2405 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM HT115 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM GEO Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM COLO320 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM LIM2537 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM HCA-7 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM COLO205 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM KM12 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM CCK81 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM SW620 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM SNU175 Homo sapiens
Ponatinib Influence on cell proliferation Cell Titer Glo assay 1.00 µM C70 Homo sapiens
Ponatinib Influence on cell migration Wound healing assay 1.00 µM DLD-1 Homo sapiens
Ponatinib Influence on cell migration Wound healing assay 1.00 µM SW48 Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM IMR-32 Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM NGP Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM NB-19 Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM SK-N-AS Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM SH-SY5Y Homo sapiens
Ponatinib Influence on cell proliferation WST-8 1.00 µM LA-N6 Homo sapiens
Ponatinib Influence on cell growth Colony formation assay 1.00 µM IMR-32 Homo sapiens