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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DIFI Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM DLD-1 Homo sapiens
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens p-STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens STAT3
Ponatinib Influence on protein activity in presence of IL-11 Western Blot 0.10 µM SW48 Homo sapiens
Ponatinib Influence on protein translocation in presence of IL-11 Fluorescent staining 0.10 µM DLD-1 Homo sapiens STAT3
Ponatinib Influence on gene expression RT-qPCR 0.10 µM DIFI Homo sapiens
Ponatinib Influence on gene expression RT-qPCR 0.10 µM DLD-1 Homo sapiens
Ponatinib Influence on gene expression RT-qPCR 0.10 µM SW48 Homo sapiens
Ponatinib Influence on cell migration Wound healing assay 0.10 µM DLD-1 Homo sapiens
Ponatinib Influence on cell migration Wound healing assay 0.10 µM SW48 Homo sapiens