| Plumbagin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
2.00 mg/kg |
DU145(xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
5.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
10.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
20.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein activity in tumor tissue |
Western Blot |
2.00 mg/kg |
DU145(xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
5.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
10.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
15.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
20.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
5.00 µM |
CWR22Rv1 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
10.00 µM |
CWR22Rv1 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
15.00 µM |
CWR22Rv1 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
20.00 µM |
CWR22Rv1 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
5.00 µM |
PC-3 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
10.00 µM |
PC-3 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
15.00 µM |
PC-3 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
20.00 µM |
PC-3 |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
5.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
10.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
15.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein-DNA interaction |
EMSA |
20.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
5.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
10.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
20.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| Plumbagin |
Influence on protein activity in tumor tissue |
Western Blot |
2.00 mg/kg |
DU145(xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3(Y705) |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
5.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(S727) |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
10.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(S727) |
|
| Plumbagin |
Influence on protein activity |
Western Blot |
20.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3(S727) |
|
| Plumbagin |
Influence on protein activity in tumor tissue |
Western Blot |
2.00 mg/kg |
DU145(xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3(S727) |
|
