Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on gene expression |
RT-qPCR |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on gene expression |
RT-qPCR |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity in presence of bortezomib |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity in presence of bortezomib |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity in presence of bortezomib |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity in presence of bortezomib |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on ROS generation |
Flow cytometry |
10.00 µM |
786-O |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on ROS generation |
Flow cytometry |
10.00 µM |
PNX0010 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell viability and proliferation |
MTT |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell viability and proliferation |
MTT |
10.00 µM |
AGS |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell cycle |
Flow cytometry |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell cycle |
Flow cytometry |
10.00 µM |
AGS |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell motility |
Migration assay |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on cell motility |
Migration assay |
10.00 µM |
AGS |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
|
|
Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
10.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
10.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
Piperlongumine |
Influence on protein phosphorylation |
Flow cytometry |
10.00 µM |
Kasumi 1 |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 |
|
Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|