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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens p-STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on gene expression RT-qPCR 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on gene expression RT-qPCR 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity in presence of bortezomib Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity in presence of bortezomib Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on protein activity in presence of bortezomib Western Blot 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on protein activity in presence of bortezomib Western Blot 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on ROS generation Flow cytometry 10.00 µM 786-O Homo sapiens
Piperlongumine Influence on ROS generation Flow cytometry 10.00 µM PNX0010 Homo sapiens
Piperlongumine Influence on cell viability and proliferation MTT 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on cell viability and proliferation MTT 10.00 µM AGS Homo sapiens
Piperlongumine Influence on cell cycle Flow cytometry 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on cell cycle Flow cytometry 10.00 µM AGS Homo sapiens
Piperlongumine Influence on cell motility Migration assay 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on cell motility Migration assay 10.00 µM AGS Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens STAT3
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens
Piperlongumine Influence on protein translocation in presence of IL-6 Confocal and high-throughput fluorescence microscopy (HTFM) 10.00 µM Stat3−/− MEF Mus musculus STAT3
Piperlongumine Influence on protein translocation in presence of IL-6 Fluorescence intensity in the nucleus (FLIN) 10.00 µM Stat3−/− MEF Mus musculus STAT3
Piperlongumine Influence on protein phosphorylation Flow cytometry 10.00 µM Kasumi 1 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-231 Homo sapiens STAT3