| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
0.30 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
0.30 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT1 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT1 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT5 |
|
| Piperlongumine |
Influence on cell growth |
MTT |
0.30 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| Piperlongumine |
Influence on cell growth |
MTT |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Piperlongumine |
Influence on cell growth |
MTT |
0.30 µM |
Hs 578T |
Homo sapiens |
|
|
|
