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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Pimozide Influence on apoptosis Western Blot 5.00 µM HuT102 Homo sapiens
Pimozide Influence on apoptosis Western Blot 10.00 µM HuT102 Homo sapiens
Pimozide Influence on apoptosis Western Blot 20.00 µM HuT102 Homo sapiens
Pimozide Influence on apoptosis Western Blot 5.00 µM HuT102 Homo sapiens
Pimozide Influence on apoptosis Western Blot 10.00 µM HuT102 Homo sapiens
Pimozide Influence on apoptosis Western Blot 20.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM Kit225 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 5.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 10.00 µM HuT102 Homo sapiens
Pimozide Influence on TRAIL/DR4 dependent apoptosis Flow cytometry- Annexin 20.00 µM HuT102 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 1.00 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 5.00 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 7.50 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 10.00 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 1.00 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability ATP-dependent luminescence assay 5.00 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability ATP-dependent luminescence assay 7.50 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability ATP-dependent luminescence assay 10.00 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability Flow cytometry- Annexin 1.00 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)
Pimozide Influence on cell viability Flow cytometry- Annexin 2.50 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)
Pimozide Influence on cell viability Flow cytometry- Annexin 5.00 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)
Pimozide Influence on cell viability Flow cytometry- Annexin 7.50 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)
Pimozide Influence on cell viability Flow cytometry- Annexin 10.00 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)
Pimozide Influence on protein activity in patient tissue Western Blot 20.00 µM lymphoma cells Homo sapiens (patient 112) p-STAT5
Pimozide Influence on protein activity in patient tissue Western Blot 20.00 µM lymphoma cells Homo sapiens (patient 112) STAT5
Pimozide Influence on protein activity in patient tissue Western Blot 20.00 µM lymphoma cells Homo sapiens (patient 112)
Pimozide Influence on apoptosis in patient tissue Flow cytometry- Annexin 20.00 µM lymphoma cells Homo sapiens (patient 112)
Pimozide Influence on protein activity in patient tissue Western Blot 20.00 µM lymphoma cells Homo sapiens (patient 706) p-STAT5