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Experiments
Compound | Investigated event | Experiment type | Concentration | Cell line | Organism | Animal model | Stat protein | Details |
---|---|---|---|---|---|---|---|---|
Paclitaxel | Influence on protein activity | Western Blot | 2.00 µM | NRK-49F | Homo sapiens | p-STAT3 | ||
Paclitaxel | Influence on protein activity | Western Blot | 4.00 µM | NRK-49F | Homo sapiens | p-STAT3 | ||
Paclitaxel | Influence on tubulointerstitial fibrosis | Immunohistochemistry | 0.30 mg/kg | kidney tissue | Mus musculus | C57BL/6 (UUO) | p-STAT3 | |
Paclitaxel | Influence on protein activity- translocation | Immunoprecipitation | 4.00 µM | NRK-49F | Homo sapiens | p-STAT3/STAT3 |