| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
10.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
10.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
PaCa-2 |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
PaCa-2 |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
Pa02C |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
Pa02C |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on cell proliferation in tumor tissue |
Average weight |
10.00 mg/kg |
Pa03C (patient derived) |
Mus musculus |
NSG |
|
|
| PG-S3-001 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
10.00 mg/kg |
Pa03C (patient derived) |
Mus musculus |
NSG |
|
|
