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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens STAT3
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens
OPB-31121 Influence on protein activity Western Blot 5.00 µM HCT116 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity Western Blot 5.00 µM HCT116 Homo sapiens STAT3
OPB-31121 Influence on protein activity Western Blot 5.00 µM HCT116 Homo sapiens
OPB-31121 Influence on protein activity Western Blot 5.00 µM HCT116 Homo sapiens
OPB-31121 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens STAT3
OPB-31121 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens
OPB-31121 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM 77211 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Huh7 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM HepG2 Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM DLD1 Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM DLD1 Homo sapiens STAT3
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM DLD1 Homo sapiens
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens