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Experiments
Compound | Investigated event | Experiment type | Concentration | Cell line | Organism | Animal model | Stat protein | Details |
---|---|---|---|---|---|---|---|---|
Galiellalactone | Influence on DNA-protein binding | EMSA | 5.00 µM | DU145 | Homo sapiens | STAT3 | ||
Galiellalactone | Influence on protein activity | Western Blot | 5.00 µM | DU145 | Homo sapiens | p-STAT3(Y705) | ||
Galiellalactone | Influence on protein activity | Western Blot | 5.00 µM | DU145 | Homo sapiens | p-STAT3(Y727) | ||
Galiellalactone | Influence on protein activity | Western Blot | 5.00 µM | DU145 | Homo sapiens | STAT3 | ||
Galiellalactone | Influence on protein activity In presence IL-6 | Luciferse activity | 5.00 µM | LNCaP | Homo sapiens | STAT3 |