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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
FLL32 Influence on apoptosis Western Blot 8.00 µM primary human cells derived from recurrent cutaneous melanoma tumors Homo sapiens patient 2 p-STAT3
FLL32 Influence on caspase dependent apoptosis in presence on caspase inhibitor Western Blot 2.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on caspase dependent apoptosis in presence on caspase inhibitor Western Blot 4.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 2.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 4.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 6.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 8.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 12.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 14.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 10.00 µM SW480 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 5.00 µM HCT-116 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 10.00 µM HCT-116 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 5.00 µM U87 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 2.50 µM U266 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 5.00 µM U266 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 2.50 µM SNU449 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 5.00 µM SNU449 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 10.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM MDA-MB-453 Homo sapiens p-STAT3 (Y705)
FLL32 Influence on protein activity Western Blot 2.00 µM A375 Homo sapiens p-STAT3 (Tyr705)
FLL32 Influence on protein activity Western Blot 4.00 µM A375 Homo sapiens p-STAT3 (Tyr705)
FLL32 Influence on protein activity Western Blot 2.00 µM Hs294T Homo sapiens p-STAT3 (Tyr705)
FLL32 Influence on protein activity Western Blot 4.00 µM Hs294T Homo sapiens p-STAT3 (Tyr705)
FLL32 Influence on protein activity Western Blot 2.00 µM A375 Homo sapiens p-STAT3 (Tyr727)
FLL32 Influence on protein activity Western Blot 4.00 µM A375 Homo sapiens p-STAT3 (Tyr727)
FLL32 Influence on protein activity Western Blot 2.00 µM Hs294T Homo sapiens p-STAT3 (Tyr727)
FLL32 Influence on protein activity Western Blot 4.00 µM Hs294T Homo sapiens p-STAT3 (Tyr727)
FLL32 Influence on protein activity Western Blot 5.00 µM SW480 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 10.00 µM SW480 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 5.00 µM HCT-116 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 10.00 µM HCT-116 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 2.50 µM U266 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 5.00 µM U266 Homo sapiens p-STAT3 (Y727)
FLL32 Influence on protein activity Western Blot 2.50 µM SNU449 Homo sapiens p-STAT3 (Y727)