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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
FLL32 Influence on apoptosis Western Blot 8.00 µM primary human cells derived from recurrent cutaneous melanoma tumors Homo sapiens patient 2 p-STAT3
FLL32 Influence on caspase dependent apoptosis in presence on caspase inhibitor Western Blot 2.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on caspase dependent apoptosis in presence on caspase inhibitor Western Blot 4.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 2.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 4.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 6.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 8.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 12.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 14.00 µM A375 Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IFNγ Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 2.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 4.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 6.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein activity in presence of IL-2 Western Blot 8.00 µM PBMC Homo sapiens p-STAT3
FLL32 Influence on protein binding affinity to DNA EMSA 10.00 µM OSA8 Canis lupus STAT3
FLL32 Influence on protein binding affinity to DNA EMSA 10.00 µM SJSA Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 2.50 µM OSA8 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM OSA8 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 10.00 µM OSA8 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 2.50 µM OSA16 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM OSA16 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 10.00 µM OSA16 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 2.50 µM D17 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM D17 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 10.00 µM D17 Canis lupus STAT3
FLL32 Influence on protein activity Western Blot 2.50 µM SJSA Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 2.50 µM U2OS Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens STAT3
FLL32 Influence on protein activity Western Blot 10.00 µM U2OS Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM A375 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM F01 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM Hs294T Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM HT144 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM MEL39 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM MEL1106 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 1.00 µM MEL1259 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 2.00 µM A375 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 2.00 µM F01 Homo sapiens STAT3
FLL32 Influence on cell apoptosis Flow cytometry 2.00 µM Hs294T Homo sapiens STAT3