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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Evodiamine Influence on protein activity in presence of IL6 Western Blot 5.00 µM HCC Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 25.00 µM HCC Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 50.00 µM HCC Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 5.00 µM Hep2 Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 25.00 µM Hep2 Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 50.00 µM Hep2 Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 50.00 µM QGY-7701 Homo sapiens p-STAT3
Evodiamine Influence on protein activity in presence of IL6 Western Blot 50.00 µM Bel-7402 Homo sapiens p-STAT3
Evodiamine Influence on protein activity in transfected cells upon presence of IL6 Western Blot 50.00 µM Hep2 Homo sapiens p-STAT3
Evodiamine Influence on tumor growth Immunohistochemistry 10.00 mg/kg Hep2 (xenograft) Mus musculus p-STAT3 (Tyr705)
Evodiamine Influence on tumor growth Immunohistochemistry 20.00 mg/kg Hep2 (xenograft) Mus musculus p-STAT3 (Tyr705)