| Dasatinib |
Influence on gene expression |
qRT-PCR |
3.30 nM |
K562 |
Homo sapiens |
|
STAT5A |
|
| Dasatinib |
Influence on gene expression |
qRT-PCR |
3.30 nM |
K562 |
Homo sapiens |
|
STAT5B |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
3.30 nM |
K562 |
Homo sapiens |
|
STAT5A |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
3.30 nM |
K562 |
Homo sapiens |
|
STAT5B |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
3.30 nM |
K562 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
Colony formation assay |
10.00 nM |
MPN |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
Colony formation assay |
1.00 nM |
ET |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
p-STAT5 |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
p-STAT5 |
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
p-STAT5 |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
STAT5 |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
STAT5 |
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
STAT5 |
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
100.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity in presence of Ruxololitinib |
Western Blot |
10.00 nM |
BaF3 JAK2 V617F |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
0.80 µM |
HepG2 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
1.00 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
4.40 µM |
Hep3B |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
5.60 µM |
HLE |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
6.50 µM |
HLF |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
6.70 µM |
Huh-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
8.50 µM |
HT-17 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
0.70 µM |
PLC/PRF/6 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on cell viability |
MTS |
14.20 µM |
Li-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.00 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.01 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.10 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
1.00 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
Sk-Hep1 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.00 µM |
Li-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.01 µM |
Li-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
0.10 µM |
Li-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
1.00 µM |
Li-7 |
Homo sapiens |
|
|
|
| Dasatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
Li-7 |
Homo sapiens |
|
|
|
