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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 1.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 1.00 µM CAES17 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM CAES17 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM CAES17 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM CAES17 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM CAES17 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 1.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 2.50 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 5.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 10.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 25.00 mg/kg EC109 (xenograft) Mus musculus BALB/c STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg EC109 (xenograft) Mus musculus BALB/c STAT3
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 7.50 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 7.50 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 7.50 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 0.25 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 0.50 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 1.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence of siRNA on STAT3 regulated genes Western Blot 15.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on STAT3 overexpression Western Blot 10.00 µM Hey Homo sapiens STAT3
Cryptotanshinone Influence on STAT3 overexpression Western Blot 10.00 µM A2780 Homo sapiens STAT3
Cryptotanshinone Influence on tumor cell growth and proliferation RT-qPCR 10.00 mg/kg Hey(xenograft) Mus musculus STAT3
Cryptotanshinone Influence on tumor cell growth and proliferation RT-qPCR 10.00 mg/kg Ovarian cancer patients tissue Homo sapiens STAT3
Cryptotanshinone Influence on tumor cell growth and proliferation RT-qPCR 10.00 mg/kg Ovarian cancer patients serum Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM BxPC‑3 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM BxPC‑3 Homo sapiens STAT3