Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
5.00 µM |
U251 SHP-2 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 TC-PTP |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-1 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.00 µM |
CAES17 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
CAES17 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
CAES17 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
CAES17 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
CAES17 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in presence of IL-6 |
Western Blot |
20.00 µM |
EC109 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Western Blot |
25.00 mg/kg |
EC109 (xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
EC109 (xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
15.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
15.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
15.00 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
7.50 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
7.50 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
7.50 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
HGC27 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
0.25 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
0.50 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence of siRNA on STAT3 regulated genes |
Western Blot |
15.00 µM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on STAT3 overexpression |
Western Blot |
10.00 µM |
Hey |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on STAT3 overexpression |
Western Blot |
10.00 µM |
A2780 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on tumor cell growth and proliferation |
RT-qPCR |
10.00 mg/kg |
Hey(xenograft) |
Mus musculus |
|
STAT3 |
|
Cryptotanshinone |
Influence on tumor cell growth and proliferation |
RT-qPCR |
10.00 mg/kg |
Ovarian cancer patients tissue |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on tumor cell growth and proliferation |
RT-qPCR |
10.00 mg/kg |
Ovarian cancer patients serum |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
BxPC‑3 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
BxPC‑3 |
Homo sapiens |
|
STAT3 |
|