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Experiments
| Compound | Investigated event | Experiment type | Concentration | Cell line | Organism | Animal model | Stat protein | Details |
|---|---|---|---|---|---|---|---|---|
| C48 | Influence on protein-DNA interaction | EMSA | 200.00 µM | SK-MEL-5 | Homo sapiens | STAT3:STAT3 | ||
| C48 | Influence on protein-DNA interaction | EMSA | 200.00 µM | SK-MEL-5 | Homo sapiens | STAT1:STAT3 | ||
| C48 | Influence on protein-DNA interaction | EMSA | 200.00 µM | SK-MEL-5 | Homo sapiens | STAT1:STAT1 | ||
| C48 | Influence on tumor growth | Tumor volume | 200.00 mg/kg | MDA-MB-468 (xenograft) | Mus musculus | athymic nude mice | ||
| C48 | Influence on tumor growth | Tumor volume | 200.00 mg/kg | MDA-MB-468 (xenograft) | Mus musculus | C3H/HeJ syngeneic mice |