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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Brevilin A Influence on PI3K/AKT pathway members Western Blot 1.25 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 2.50 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 5.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 20.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 1.25 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 2.50 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 5.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 10.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT pathway members Western Blot 20.00 µM CNE-2 Homo sapiens
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 20.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 10.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on PI3K/AKT and STAT3 signaling pathways Western Blot 20.00 mg/kg CNE-2 (xenograft) Mus musculus BALB/c nude
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A2058 Homo sapiens