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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Brassinin Influence on protein activity in tumor tissue Immunohistochemistry 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu p-STAT3
Brassinin Influence on protein activity in tumor tissue in presence of paclitaxel Immunohistochemistry 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu p-STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM U266 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM DU145 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM A549 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM K526 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM SCC4 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM H460 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM PC-9 Homo sapiens STAT3
Brassinin Influence on protien nuclear translocation EMSA 100.00 µM A549 Homo sapiens STAT3
Brassinin Influence on protien nuclear translocation EMSA 200.00 µM A549 Homo sapiens STAT3
Brassinin Influence on protien nuclear translocation EMSA 300.00 µM A549 Homo sapiens STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM H1299 Homo sapiens STAT3
Brassinin Influence on protein activity in PIAS-3 silenced cells Western Blot 300.00 µM A549 Homo sapiens STAT3
Brassinin Influence on protein activity in SOCS-3 transfected cells Western Blot 300.00 µM A549 Homo sapiens STAT3
Brassinin Influence on cell apoptosis in STAT3 transfected cells Western Blot 300.00 µM MEF Mus musculus STAT3
Brassinin Influence on protein activity in tumor tissue Western Blot 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu STAT3
Brassinin Influence on protein activity in tumor tissue in presence of paclitaxel Western Blot 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu STAT3
Brassinin Influence on protein activity Western Blot 300.00 µM U266 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM DU145 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM A549 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM K526 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM SCC4 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM H460 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM PC-9 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity Western Blot 300.00 µM H1299 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity in PIAS-3 silenced cells Western Blot 300.00 µM A549 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on protein activity in SOCS-3 transfected cells Western Blot 300.00 µM A549 Homo sapiens p-STAT3 (Y705)
Brassinin Influence on cell apoptosis in STAT3 transfected cells Western Blot 300.00 µM MEF Mus musculus p-STAT3 (Y705)
Brassinin Influence on protein activity in tumor tissue Western Blot 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu p-STAT3 (Y705)
Brassinin Influence on protein activity in tumor tissue in presence of paclitaxel Western Blot 180.00 mg/kg A549 (xenograft) Mus musculus athymic nu/nu p-STAT3 (Y705)