| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
10.00 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
p-STAT3(Tyr705) |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
p-STAT3(Tyr705) |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on apoptosis |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on apoptosis |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| Berbamine |
Encephalitogenic T cell response |
Measurement by cpm as detected by a MicroBeta counter |
10.00 μg/ml |
Spinal cord tissue |
Mus musculus |
c57BL/6 |
|
|
