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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM SK-MEL-28 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Cell viability MTS Assay 10.00 µM NHDF Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on apoptosis Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on apoptosis Western Blot 10.00 µM A2058 Homo sapiens