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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity Western Blot 0.05 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.10 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.05 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity Western Blot 0.10 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of SN50 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of SN50 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity Western Blot 0.30 µM MDA-MB 231 Homo sapiens STAT3
Auranofin Influence on protein activity Western Blot 0.50 µM MDA-MB 231 Homo sapiens STAT3
Auranofin Influence on protein activity Western Blot 1.00 µM MDA-MB 231 Homo sapiens STAT3
Auranofin Influence on protein activity Western Blot 0.30 µM MDA-MB 231 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.50 µM MDA-MB 231 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 1.00 µM MDA-MB 231 Homo sapiens p-STAT3
Auranofin Influence on protein activity in presence of NAC Western Blot 1.00 µM MDA-MB 231 Homo sapiens STAT3
Auranofin Influence on protein activity in presence of NAC Western Blot 1.00 µM MDA-MB 231 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.50 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 1.00 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 2.00 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 0.50 µM KBM5-T315I Homo sapiens
Auranofin Influence on protein activity Western Blot 1.00 µM KBM5-T315I Homo sapiens
Auranofin Influence on protein activity Western Blot 2.00 µM KBM5-T315I Homo sapiens
Auranofin Influence on protein activity Western Blot 0.50 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 1.00 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 2.00 µM KBM5 Homo sapiens
Auranofin Influence on protein activity Western Blot 0.50 µM KBM5-T315I Homo sapiens
Auranofin Influence on protein activity Western Blot 1.00 µM KBM5-T315I Homo sapiens