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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Auranofin Influence on cell viability MTS 0.05 µM U266 Homo sapiens
Auranofin Influence on cell viability MTS 0.10 µM U266 Homo sapiens
Auranofin Influence on cell viability MTS 0.50 µM U266 Homo sapiens
Auranofin Influence on cell viability MTS 1.00 µM U266 Homo sapiens
Auranofin Influence on cell morphology Giemsa staining 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis Flow cytometry Annexin V-FITC 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Flow cytometry DNA content 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on cell cycle Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on caspase activation Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis-associated proteins in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity Western Blot 0.05 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.10 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein activity Western Blot 0.05 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity Western Blot 0.10 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens STAT3
Auranofin Influence on protein activity in presence of IL-6 Western Blot 0.05 µM U266 Homo sapiens p-STAT3
Auranofin Influence on protein-DNA interaction ELISA 0.05 µM U266 Homo sapiens
Auranofin Influence on protein-DNA interaction ELISA 0.10 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of TNF-α Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of SN50 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on protein activity in presence of SN50 Western Blot 0.05 µM U266 Homo sapiens
Auranofin Influence on apoptosis in transfected cells Immunofluorescence 0.05 µM U266 pEGFP-C1-neo Homo sapiens
Auranofin Influence on cell viability MTS 0.05 µM U266 pEGFP-C1-neo Homo sapiens
Auranofin Influence on apoptosis in transfected cells Immunofluorescence 0.05 µM U266 pEGFP-C1-mcl-1 Homo sapiens
Auranofin Influence on cell viability MTS 0.05 µM U266 pEGFP-C1-mcl-1 Homo sapiens