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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Andrographolide Influence on protein activity Western Blot 1.00 µM DU145 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 5.00 µM DU145 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 10.00 µM DU145 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 20.00 µM DU145 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 1.00 µM LNCaP Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 5.00 µM LNCaP Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 10.00 µM LNCaP Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 20.00 µM LNCaP Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 25.00 µM AsPC-1 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 25.00 µM Panc-1 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of gemcitabine Western Blot 10.00 µM AsPC-1 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of gemcitabine Western Blot 10.00 µM Panc-1 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of LPS Western Blot 50.00 µM RAW264.7 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of LPS Western Blot 10.00 µM RAW264.7 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of LPS Western Blot 2.00 µM RAW264.7 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 7.50 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity Western Blot 30.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity Luciferase activity 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide derivative Influence on protein-protein interaction in presence of IFNγ Western Blot 10.00 µM AD-293 Homo sapiens STAT3
Andrographolide derivative Influence on CCl4-induced inflammation RT-qPCR 30.00 mg/kg liver Mus musculus BALB/c STAT3
Andrographolide derivative Influence on protein-protein interaction in presence of IFNγ Western Blot 10.00 µM AD-293 Homo sapiens p-STAT3(Y705)
Andrographolide Influence on protein activity in presence of LPS Western Blot 50.00 µM RAW264.7 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity in presence of LPS Western Blot 10.00 µM RAW264.7 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity in presence of LPS Western Blot 2.00 µM RAW264.7 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity Western Blot 7.50 µM MDA-MB-231 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity Western Blot 30.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity Western Blot 1.00 µM DU145 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 5.00 µM DU145 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 10.00 µM DU145 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 20.00 µM DU145 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 1.00 µM LNCaP Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 5.00 µM LNCaP Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 10.00 µM LNCaP Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 20.00 µM LNCaP Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 25.00 µM AsPC-1 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 25.00 µM Panc-1 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of gemcitabine Western Blot 10.00 µM AsPC-1 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of gemcitabine Western Blot 10.00 µM Panc-1 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of LPS Western Blot 50.00 µM RAW264.7 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of LPS Western Blot 10.00 µM RAW264.7 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of LPS Western Blot 2.00 µM RAW264.7 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 7.50 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 30.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)