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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD9150 Influence on protein activity Western Blot 0.25 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 0.50 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 1.00 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 2.50 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 5.00 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 0.25 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 0.50 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 1.00 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 2.50 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 5.00 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 10.00 µM AS Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 0.25 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 0.50 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 1.00 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 2.50 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 5.00 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity Western Blot 10.00 µM IMR32 Homo sapiens p-STAT3(Ser727)
AZD9150 Influence on protein activity in tumor tissue Western Blot 100.00 mg/kg NGP(xenograft) Mus musculus p-STAT3(Ser727)