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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD9150 Influence on protein activity Western Blot 0.25 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 0.50 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 1.00 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 2.50 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 5.00 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 0.25 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 0.50 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 1.00 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 2.50 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 5.00 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 10.00 µM AS Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 0.25 µM IMR32 Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 0.50 µM IMR32 Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 1.00 µM IMR32 Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 2.50 µM IMR32 Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 5.00 µM IMR32 Homo sapiens STAT3
AZD9150 Influence on protein activity Western Blot 10.00 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.25 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.50 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 1.00 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 2.50 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 5.00 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 10.00 µM IMR32 Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.25 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.50 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 1.00 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 2.50 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 5.00 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 10.00 µM AS Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.25 µM NGP Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 0.50 µM NGP Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 1.00 µM NGP Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 2.50 µM NGP Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 5.00 µM NGP Homo sapiens STAT3
AZD9150 Infleunce on mRNA expression level RT-PCR 10.00 µM NGP Homo sapiens STAT3
AZD9150 Influence on protein activity in tumor tissue Western Blot 100.00 mg/kg NGP(xenograft) Mus musculus STAT3
AZD9150 Influence on protein activity Western Blot 0.25 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 0.50 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 1.00 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 2.50 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 5.00 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 10.00 µM NGP Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 0.25 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 0.50 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 1.00 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 2.50 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 5.00 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 10.00 µM AS Homo sapiens p-STAT3(Tyr705)
AZD9150 Influence on protein activity Western Blot 0.25 µM IMR32 Homo sapiens p-STAT3(Tyr705)